搜狐足彩

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添加时间:2016-04-08    阅读次数:4590

搜狐足彩 [ZHAIYAO] MUDE:BIJIAOSHUIZHIJIANJI、PUTONGSANJIDEYAOXIAOYIJIXINFAPAOZHIYUCHAOWEIFENSUIDUIQIYAOXIAODEYINGXIANG。FANGFA:YONGBT-1500XINGLIXINCHENJIANGSHILIDUFENBUYICEDINGLESHENG、ZHISHUIZHICHAOWEISANDELIDU。TONGGUOXIAOSHUKANGNINGXUE、KANGXUESHUANZUOYONG,BIJIAOLESHUIZHISISHUIJIANJI1/2JIANJIJILIANGDEPUTONGSAN、CHAOWEISAN、ZHISHUIZHICHAOWEISANDEYAOXIAO。BINGDUIQIANQUANXINGJINXINGLEKAOCHA。JIEGUO:GONGSHIPINYAOXIAOYOUQIANGDAORUOWEIZHISHUIZHICHAOWEISAN、SHENGSHUIZHICHAOWEISAN、SHENGSHUIZHISAN、SHENGSHUIZHISHUIJIANJI、DUIZHAOZU。JIELUN:SHUIZHIJINGCHAOWEIFENSUI,YOUQISHIXINFAPAOZHIHOUCHAOWEIFENSUI,KEMINGXIANGAISHANQIWEI、KOUGAN,TIGAOYAOXIAO。

搜狐足彩 [GUANJIANCI] SHUIZHI;XINFAPAOZHI;CHAOWEIFENSUI;ZENGXIAO

搜狐足彩 [ZHONGTUFENLEIHAO]  R283.1   [WENXIANBIAOSHIMA]B[WENZHANGBIANHAO] 1001-5302(2001)04-0241-04

搜狐足彩 SHUIZHIZUOWEIJINGDIANDEPOXUEZHUYUYAO,JINDAIZAIZHONGYILINCHUANGYUZHONGCHENGYAOSHENGCHANZHONGDEDAOLEYULAIYUGUANGFANDEYINGYONG,BINGCHENGWEILEYIZHONGSHIJIEXINGYAOWU。JINGQIANQIGONGZUO,CHUBUZHENGMINGSHUIZHIDEZHULIUYAOYONGPINZHONGWEIMAHUANG(KUANTIJINXIANZHIWhit mania pigra Whit man);QIESIRUYAOYOUYU《YAODIAN》GUIDINGDEQIEDUANRUYAO;SHENGYONGZAIHUOXUEHUAYUDENGYAOXIAOFANGMIAN,YOUYUCHUANTONGTANGZHIPIN;ANXINFAZHICHENGDEZHISHUIZHINENGZAIGAISHANYUANYAOQIWEIDETONGSHI,JIAOHAODEBAOCUNQINEIZAICHENGFEN,QIERONGCHUXIAOGUOJIKANGNINGXUE、KANGXUESHUAN、JIANGDIXUEXIAOBANJUJILV、GAISHANWEIXUNHUAN、JIANGDANGUCHUNDENGYAOXIAOXUEZHIBIAO,JUNYOUYUCHUANTONGTANGZHISHUIZHI,BUFENZHIBIAOYEYOUYUSHENGSHUIZHI,YOUBAOZHIZENGXIAODEQUSHI[1]。DANSHUIZHIZAILINCHUANGYINGYONGZHONGRUTANGJIWEILIENANFU,YIFANWEIBAIWEI。LINCHUANGZHONGYIYOUYANMOHUOZHUANGJIAONANGTUNFUXIAOYOUDEJINGYAN。

JINJINIANYOUYUCHAOWEIFENSUIJISHUDEFAZHAN,KEDADAOSHIDONG、ZHIWUXIBAO90%YISHANGPOBIDEXIDU。YOUYULIDUDEJIANXIAO,YEYOULIYUGAISHANYAOWUDEQIWEIJIFUYONGKOUGAN。JIANYUSHUIZHIJINGPAOZHIHECHAOWEIFENSUIHOUYOUWUYAOXIAOYUYINGYONGFANGMIANDEYOUSHI,WEIJIANBAODAO,BIZHEDUICIZUOLECHUBUDESHIYANYANJIU。

1SHIYANCAILIAO

1.1GONGSHICAILIAO

搜狐足彩 SHUIZHIGOUZISHANDONGSHENGLIYIYUAN,JINGLIDINGGE、LIFENGLAOSHIJIANDINGWEIMAHUANG(KUANTIJINXIANZHIWhit mania pigra Whitman)。

搜狐足彩 1.2GONGSHIPINZHIBEI

SHUIZHISI:YUANYAOCAITIAOQUZAZHI,CAJING,GAISHISHABULVERUNHOUQIE2~3mmXISI。ZAIQIEZHIGUOCHENGZHONGFAXIAN,BUFENYAOCAIZHONGJIANTIANCHONGYOUBAISEJIEJINGXINGFENMO,KOUCHANGWUXIAN、SEWEI、CHUBUYINXIANGWEISHIGAO,QIESILIANGGANHOUGUOSHAIKEDABUTUOLUO。JINGZIWAIDENGZHAOSHE45minHOUMIBIBEIYONG。

SHENGSHUIZHISHUIJIANYE:JINGSHUIZHISI2.6g,JIA10BEILIANGSHUIJINPAO30min,WEIFEI30min,GUOLV,YAOZHAJIA8BEILIANGSHUI,WEIFEI30min,GUOLV,HEBINGLVYE,DINGRONG100ml,NONGDUWEI26˙ml-1。

SHENGSHUIZHIPUTONGSAN:JINGSHUIZHISIJINGFENSUIYANMOGUO100MUSHAI。

SHENGSHUIZHICHAOWEISAN:JINGSHUIZHISIJINGSQW-6XINGSANQINGWEIFENJIFENSUI。CHULIAOWENDU35~40℃。

ZHISHUIZHICHAOWEISAN:JINGSHUIZHISIJIURUNFUZHIPAOZHIHOU,SQW-6XINGSANQINGWEIFENJIFENSUI。CHULIAOWENDUTONGSHANG。

3ZHONGSANJIJUNPINGPUYIBOCENG,JINGZIWAIDENGZHAOSHE45minHOU,MIQIEBAOCUNBEIYONG。

1.3  SHIYANDONGWUYUYIQI

KUNMINGZHONGXIAOSHU(SHANDONGZHONGYIYAODAXUEDONGWUFANGTIGONG):SQW-6XINGSANQINGWEIFENJI;BT-1500XINGLIXINCHENJIANGSHILIDUFENBUYI。

2 SHIYANFANGFAYUJIEGUO

1.1SHUIZHICHAOWEISANLIDUDECEDING

AN《YAODIAN》GUIDING,SHUIZHIPUTONGSANDELIDUWEI(150±6)µm。SHENG、ZHISHUIZHICHAOWEISANDELIDUJINGBT-1500XINGLIXINCHENJIANGSHILIDUFENBUYICEDING,JIEGUOJIANBIAO1、BIAOMIANHUA。SHIYANBIAOMING,SHENG、ZHISHUIZHIJINGWEIFENJIFENSUI,KESHIQIZHONGWEIJINGFENBIEDADAO10.24µmHE7.79µm;ZUIDALIJINGFENBIEWEI72µmHE24.81µm;50%DELIDUZAI10µmHE8µmYIXIA,90%DELIDUZAI50µmHE23µmYIXIA,QUENENGDADAOCHAOWEIDEXIAOGUO,ERQIEJINGXINFAPAOZHIHOUGENGLIYUFENSUI,QILIDUMINGXIANXIAOYUSHENGSHUIZHI。

BIAO1SHENGSHUIZHICHAOWEIFENLIDUFENBUCESHIJIEGUO

搜狐足彩 LIJING        QUJIANPINLV       LEIJIPINLV

搜狐足彩 /µm           /%               /%

0.00~1.00       3.33            3.30

1.00~2.00       4.70            8.80

2.00~3.00       4.93            12.93

3.00~4.00       5.38            18.32

4.00~5.00       5.27            23.59

5.00~6.00       4.71            28.30

6.00~7.00       5.40            33.70

7.00~8.00       5.79            39.49

8.00~9.00       5.50            44.99

搜狐足彩 9.00~10.00       4.23            49.22

10.00~11.00       3.86            53.08

搜狐足彩 11.00~12.00       0.72            53.80

搜狐足彩 12.00~13.00       0.00           53.80

搜狐足彩 13.00~14.00       0.78            54.58

搜狐足彩 14.00~15.00       3.15            57.73

15.00~20.00       10.59            68.31

20.00~30.00       20.19            88.50

搜狐足彩 30.00~40.00       1.13            89.63

搜狐足彩 40.00~50.00       1.02            90.65

50.00~60.00       6.19            96.84

搜狐足彩 60.00~70.00       3.05            99.89

搜狐足彩 70.00~72.00       0.11            100.00

72.00~73.00       0.00            100.00

73.00~74.00       0.00            100.00

搜狐足彩 ZHU:ZHONGWEIJING10.24µm   ZUIDALIJING72µm

 

搜狐足彩 2.2   GONGSHIPINDUIXIAOSHUNINGXUESHIJIANDEYINGXIANGQUTIZHONG(28±3)gDECHENGNIANXIONGXINGXIAOSHU,SUIJIFENWEI5ZU。SHUIZHIJIANJIZUYI0.4mg˙g-1JILIANGGUANWEI。3ZHONGSANJIZUMEITIANGUANWEILINSHIPEICHENG13mg˙ml-1DEHUNXUANYE,YI0.2mg˙g-1DEJILIANGGUANWEI(JIANJIDE1/2LIANG)。YONGSHENGLIYANSHUIZUODUIZHAO。MEITIAN3CI,LIANXUJIYAO3d ,DI4TIANJIYAO1hHOU,CONGXIAOSHUYANNEIPIQIUHOUJINGMAICONGQUXUE,ANMAOXIGUANFA[2],CEDINGGEZUXIAOSHUDENINGXUESHIJIAN,JINGtJIANYANTONGJIFENXI,JIEGUOJIANBIAO3。SHIYANBIAOMING,SHUIZHIJIANJIYUSHUIZHISANJIJUNYOUQUEQIEDEKANGNINGHUOXING。1/2JILIANGDESANJI,QIKANGNINGXIAOGUOYOUYUTANGJI。CHAOWEISANDEKANGNINGHUOXINGYOUYOUYUPUTONGSANDEQUSHI,ZHISHUIZHICHAOWEISANYOUMINGXIANYOUYUSHENGSHUIZHICHAOWEISAN。TISHISHUIZHIYONGXINFAPAOZHIHECHAOWEIFENSUIHOUYOULIYUZENGQIANGQIKANGNINGHUOXING。

BIAO2  ZHISHUIZHICHAOCEFENLIDUFENBUCESHIJIEGUO

搜狐足彩 LIJING        QUJIANPINLV       LEIJIPINLV

/µm           /%               /%

0.00~1.00       2.59            2.59

搜狐足彩 1.00~2.00       4.19            6.77

2.00~3.00       6.51           13.28

3.00~4.00       5.22            18.50

4.00~5.00       12.06            30.56

搜狐足彩 5.00~6.00       6.20            36.75

6.00~7.00       7.03            43.79

搜狐足彩 7.00~8.00       6.26            50.05

8.00~9.00       6.85            56.89

9.00~10.00       2.84            59.73

10.00~11.00       3.51            63.24

搜狐足彩 11.00~12.00       0.64            63.88

12.00~13.00       0.00           63.88

13.00~14.00       0.72            64.60

14.00~15.00       2.77            67.37

15.00~20.00       4.09            71.46

20.00~30.00       4.75            76.21

30.00~40.00       1.99            78.20

搜狐足彩 40.00~50.00       3.38            81.58

50.00~60.00       2.16            83.74

60.00~70.00       1.92            85.66

搜狐足彩 70.00~72.00       4.61            90.27

搜狐足彩 72.00~73.00       6.17            96.43

搜狐足彩 73.00~74.00       3.57            100.00

ZHU:ZHONGWEIJING7.97µm   ZUIDALIJING24.81µm

 

BIAO3  GONGXIAOSHIPINDUIXIAOSHUNINGXUESHIJIANDEYINGXIANG

ZUBIE             n         JILIANG       NINGXUESHIJIAN         p

                         /mg˙g-1        /min

搜狐足彩 SHENGLIYANSHUI         10        0.4        2.96±1.43

搜狐足彩 SHENGSHUIZHISHUIJIANJI     13        0.4        4.95±2.32       <0.05()

SHENGSHUIZHIPUTONGJI     14        0.2        6.23±2.73       >0.05()

SHENGSHUIZHICHAOWEISAN     13        0.2        6.33±2.60       >0.05()

搜狐足彩 ZHISHUIZHICHAOWEISAN     13        0.2        9.38±2.19       <0.01()

搜狐足彩 ZHU:()SHIGAIZUYUSHANGYIZUBIJIAO

2.3  GONGSHIPINDUIXIAOSHUCHUXUESHIJIANDEYINGXIANG

QUTIZHONG(28±3)gDECHENGNIANXIONGXINGXIAOSHU,SUIJIFENWEI5ZU。YISHANGFAXIANGTONGJILIANGJIXIAOSHUGUANWEI3d,MEITIAN2CI,DI4TIANJIYAO1h,YONGJIANWEIFA[2]CEDINGGEZUXIAOSHUJIANWEI5mmDECHUXUESHIJIAN,JIEGUOJIANBIAO4。SHIYANBIAOMING,SHENGSHUIZHISHUIJIANYEYUDUIZHAOZUXIANGBI,SUIYOUZUOYONGZENGQIANGDEQUSHIDANWUXIANZHUXINGCHAYI,ERPUTONGSANJIZUCHENGXIANZHUXINGCHAYI,LIANGZHONGCHAOWEISANJUNWEIJIXIANZHUXINGCHAYI,ZHICHAOWEISANGENGYOU。

搜狐足彩 BIAO4  GONGSHIPINDUIXIAOSHUCHUXUESHIJIANDEYINGXIANG

ZUBIE             n         JILIANG       NINGXUESHIJIAN         p

                         /mg˙g-1        /min

SHENGLIYANSHUI         10        0.4        7.95±2.58

SHENGSHUIZHISHUIJIANJI     10        0.4        10.28±3.19       >0.05()

SHENGSHUIZHIPUTONGSAN     12        0.2        14.32±7.08       <0.05()

SHENGSHUIZHICHAOWEISAN     12        0.2        15.42±5.09       <0.01()

搜狐足彩 ZHISHUIZHICHAOWEISAN     10        0.2        16.45±4.55       <0.01()

ZHU:()SHIYUNSZUBIJIAO

2.4 GONGSHIPINDUIXIAOSHUTINEIKANGSHUANZUOYONGDEYINGXIANG

KANGSHUANSHIYANFANGFAXUEYANJIURENWEI,ZAI(37±1)℃DESHENGLIYANSHUIZHONG,CEDINGXIAOSHUWEICHUXUESHIJIAN,YUSHUJINGDONGMAIPANGLUXUESHUANXINGCHENGFAJUYOUHENHAODEPINGXINGXING。KEZUOWEIYIZHONGJIANBIANYIXINGDEKANGXUESHUANXINGCHENGYAOWUDETINEICHUSHAIFAYONGYUSHIYAN[3]。QUTIZHONG(20±2)gDEXIONGXINGXIAOSHUSUIJIFENWEI5ZU,YIJIDINGJILIANGGUANWEI3d,DI4TIANJIYAO1hHOU,JIANGXIAOSHUGUDING,JUWEIJIAN3mmCHUJIANDUAN,CHUIZHIFANGFANG(37±1)℃SHENGLIYANSHUIZHONG,SHIWEIDUANZAIYEMIANXIA3cm,JILUCHUXUESHIJIAN,JIEGUOJIANBIAO5。SHIYANBIAOMING,TINEIKANGSHUANZUOYONG,YEYICHAOWEISANWEIYOU,DANSHENG、ZHIPINZHIJIANDECHAYIBUMINGXIAN。

BIAO5GONGSHIPINDUIXIAOSHUTINEIKANGSHUANZUOYONGBIJIAO

ZUBIE             n         JILIANG       NINGXUESHIJIAN         p

                         /mg˙g-1        /min

SHENGLIYANSHUI         10        0.3ml        0.95±0.22

SHENGSHUIZHISHUIJIANJI     10        0.390        1.09±0.25       >0.05()

SHENGSHUIZHIPUTONGSAN     12        0.195        1.24±0.59       >0.05()

SHENGSHUIZHICHAOWEISAN     10        0.195        1.66±0.76       <0.05()

ZHISHUIZHICHAOWEISAN     10        0.195        1.69±0.53       <0.01()

搜狐足彩 ZHU:()SHIYUNSZUBIJIAO

2.4DUIXIAOSHUANQUANXINGDEKAOCHA

SHUIZHIJINGPAOZHIHECHAOWEIFENSUIHOUYAOXIAOYOUSUOZENGQIANG,QIDUXINGSHIFOUZENGDA?WEICIKAOCHALEGONGSHIPINDUIXIAOSHUDEANQUANXING。QUTIZHONG(20±2)gDEJIANKANGXIAOSHU80ZHI,SUIJIFENWEI4ZU,1ZUJIYU1300/mg˙ml-1DESHUIJIANYE,0.4ml/ZHI,3CI/d,1.56g˙d-1(XIANGDANGYU《YAODIAN》GUIDINGDECHENGRENMEIRITANGJIFUYONGLIANGDE200BEI)。QIYU3ZUFENBIEJIYU130/mg˙ml-1DESHENGSHUIZHIPUTONGTONGSAN、CHAOWEISANHEZHISHUIZHICHAOWEISAN0.3ml/ZHI,3CI/d,117mg˙d-1(CIWEINENGTONGGUOGUANWEIQIDESANJIZUIDAJILIANG,XIANGDANGYU《YAODIAN》GUIDINGCHENGRENMEIRIFUFENMOLIANGDE30BEI),JIYAOHOUGUANCHA1ZHOU,JIEGUOXIAOSHUHUODONG、FENBIAN、MAOSEZHENGCHANG,WUSIWANG。MEIZUPINGJUNTIZHONGZENGJIA6~8g,SHUOMINGSHUIZHIJINGXINFAPAOZHIHECHAOWEIFENSUIHOUYONGYAOSHIANQUANDE。GAIJIEGUOYUQIANQIGONGZUOHESHUIZHIDEYAJIXINGDUXINGBAODAO[4]XIANGYIZHI,ZHICHILINCHUANGZHONGRENWEI“SHUIZHIXILIAOXIAOZHUOZHUDEWUDUPIN”DEGUANDIAN。

3 XIAOJIEYUTAOLUN

搜狐足彩 3.1SHUIZHISIRUYAO,JIYOULIYUQIYAOWUCHENGFENDEJIAN CHU,YOUYOULIYUQUCHUSHUIZHITINEIRENWEICHANRUZAZHI,YOUYU《YAODIAN》GUIDINGDEQIEDUANRUYAO。

3.2 SHENGSHUIZHIJINGCHAOWEIFENSUI,90%DELIDUWEIPUTONGSANDE1/4,50%DELIDUWEIPUTONGSANDE1/15,QIEYANSEBIANQIAN,XINGWEIJIANGDI,ZHIDIXINI,LIYUTUNFU。1/2JIANJIJILIANGDEKANGNINGXUE、KANGXUESHUANZUOYONGYOUYUSHUIZHISIJIANJI,KENDINGGENGYOUYU《ZHONGGUOYAODIAN》2000NIANBANGUIDINGDESHUIZHIDUANJIANJI,ZHENGMINGDUOSHULINCHUANGJINGYANRENWEISHUIZHIFUSANXIAOYOUSHIZHENGQUEDE,LIYONGCHAOWEIJISHUJIANGGENGYOULIYUSHUIZHIYAOXIAODEFAHUI。

1.3SHUIZHIJINGXINFAPAOZHIHOU,YOULIYUJIAOZHENGQIQIWEI,CHAOWEIFENSUIHOUQILIDUYEXIAOYUSHENGSHUIZHI,ZUIDALIJINGWEISHENGSHUIZHICHAOWEIFEN1/3,JINWEI24µm。SHIYANYAOXIAOZHIBIAOZAI3ZHONGSANJIZHONGCHENGZUIYOUQUSHI,ZHIDEJINYIBUSHENRUYANJIUJITUIGUANGYINGYONG。

1.4SUIRANYAOWULIDUDEJIANXIAO,YOULIYUQIRONGJIEXISHOUBINGGAISHANQIWEIKOUGAN,DANYEHUIYINQIBIAOMIANNENGHEWENDINGXINGDENGFANGMIANDEBIANHUA。ZHISHUIZHICHAOWEIFENDEWENDINGXINGJIZUIJIALIDUFANWEIDENGWENTI,HAIYOUDAIYUJINYIBUYANJIU。

1.5SHUIZHIZUOWEIYIZHONGSHIJIEXINGYAOWU,YANJIUZUIDUODEPINZHONGSHIRIBENYIZHI(Hirude nipponica  Whitman),ERWOGUOLINCHUANGYONGYAODEZHULIUSHANGPINSHIKUANTIJINXIANZHI。GAIPINZHONGYOUXIAOBUWEIJIYOUXIAOCHENGFENDEYANJIU,MUQIANJIJINKONGBAI。SHENRUYANJIUQICHENGFEN,JIANGYOULIYUYINPIANZHILIANGDEKONGZHIHEPAOZHIYUANLIDEYANJIU,CILEITANSUOMUQIANZHENGZAIJINXINGZHIZHONG。

[CANKAOWENXIAN]

[1]LVWENMEI,WANGQI,WUJIBIAO,DENG.SHUIZHIYINPIANPAOZHIYANJIU.ZHONGYAOCAI,1996.19(4):294

[2]LIYIKUI.ZHONGYAOYAOLISHIYANFANGFAXUE.SHANGHAI:SHANGHAIKEXUEJISHUCHUBANSHE,1991.494.

[3]顾云,孟娟如.介绍一种简易的抗血栓药物体内筛选法.中国药理学通报,1991,7(4):317
搜狐足彩 [4]陈小野,邹世洁.水蛭的医学研究概述.成都中医学院学报.1987,10 (5):51.

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